November 15, 1875, Sisters Euphemia Gaertner, Fortunata Honkamp and Franziska Dreisvogt arrived in Effingham, Illinois. They were greeted by the pastor and people of St. Anthony's parish church. The three Sisters rented one room in the two-story frame house of the Wintrup family, located at 506 North Third Street.
Soon they were going about the area serving the poor and the sick, without thought of any return. All were welcomed, regardless of religion. Doctors soon recognized that their care was truly professional, as well as generous and concerned. Families trusted them with their loved ones. They knew neither race nor creed - only God's loved ones; and they served them all.